International Journal of Cardiovascular Sciences. 29/set/2020;33(5):437-8.
Translational Medicine – New Frontiers in Cardiology
Protásio Lemos da Luz
, Claudio Tinoco Mesquita
Translational medicine is defined by the European Society for Translational Medicine (EUSTM) as “an interdisciplinary branch of the biomedical field supported by three main pillars: benchside, bedside, and community. Frequently, translational medicine dedicated to cardiology is known as translational cardiology. The International Journal of Cardiovascular Sciences is dedicating a special thematic issue on translational cardiology due to the significant importance of this field in the last years. Searching PubMed for the keywords “translational” and “cardiology,” the number of papers on translational cardiology were no more than 10 per year in mid-80’s, with an increase to around 50 papers per year in mid-90’s, 200 articles per year in the 2000’s and, thereafter, a significant exponential increase in the absolute number of publications, close to 2,000 papers/year in 2019 ( ). Cardiac journals are increasingly accepting translational papers covering different aspects of this exciting field, so diverse as cardiotoxic mechanisms targeting RNA with antisense oligonucleotides and small interfering RNA in amyloidosis or nitrosative stress as a modulator of inflammatory change in Takotsubo Syndrome to name a few.
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