International Journal of Cardiovascular Sciences. 28/jun/2023;36:e20220022.

Coronary Artery Disease in Women: Getting to Know Gender Related Disparities

Ana Gilabert-Garcia ORCID logo , Cristina Cristina Villarreal Guerrero ORCID logo , Rodrigo Dagio-Cuéllar ORCID logo , Jorge Luis Bermudez-Gonzalez ORCID logo , Arantza Marie Perez-Partida ORCID logo , Joaquin Berarducci ORCID logo , Javier Ivan Armenta-Moreno ORCID logo , Jose Luna-Alvarez-Amezquita ORCID logo , Juan Ignacio Straface ORCID logo , Nilda Espinola-Zavaleta ORCID logo , Erick Alexanderson ORCID logo

DOI: 10.36660/ijcs.20220022

Abstract

Coronary artery disease (CAD) and ischemic heart disease (IHD) are often indistinctly used terms. Both combined have generated, over the past years, concerns about sex disparities in their presentation. From an epidemiological perspective, females have several disadvantages regarding the prevention, diagnosis, and treatment of CAD. Most of the general cardiovascular risk factors affect women more frequently, or with a higher morbidity and mortality association. Besides, atypical manifestations of the disease and uncommon forms of CAD represent a diagnostic challenge for clinicians. Even if current treatments for CAD have no apparent sex bias, women representation in clinical trials and treatment patterns analyzed in clinical practice refuse this statement. Several disparities are caused by inevitable sex-particularities, but many of them are more social, cultural, and dogmatic beliefs that have to be addressed and overhaul.

Coronary Artery Disease in Women: Getting to Know Gender Related Disparities

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