Introduction Aortic stenosis is one of the most common and serious valve diseases, particularly affecting the elderly population. This progressive condition, characterized by the narrowing of the aortic valve, leads to obstructed blood flow from the heart, resulting in significant morbidity and mortality if left untreated. Traditionally, the gold standard for treating severe symptomatic aortic stenosis has been surgical aortic valve replacement (SAVR), which has proven to be highly effective. However, SAVR is associated with substantial surgical risks, particularly in […]

Introduction Coronary artery disease is the leading cause of death worldwide and presents a great social and financial burden for healthcare systems. Although the entire process of atherosclerotic plaque formation and progression to myocardial infarction is driven by inflammation, few therapies targeting this mechanism are available (e.g., colchicine)., In this context, foods with bioactive properties, such as chocolate, have drawn interest for their potential cardiovascular benefits. Prospective studies and meta-analyses have demonstrated that chocolate consumption may reduce the incidence of […]

Abstract Background: Chronic kidney disease (CKD) is a condition characterized by abnormalities in kidney structure or function lasting more than 3 months. CKD is known to increase the risk of cardiovascular events, which may be predicted by electrocardiography (ECG) abnormalities, such as left ventricular hypertrophy (LVH). ECG is widely used in under-resourced health care settings due to its practicality and accessibility. Objective: This study aimed to analyze the relationship between LVH and CKD using ECG. Methods: This analytical observational study […]

Abstract Background: C-reactive protein (CRP) is a widely available inflammatory biomarker. Its prognostic role during hospitalization in patients with acute heart failure (HF) remains unclear. Objective: To assess whether CRP measured at hospital admission predicts in-hospital mortality in patients with acute HF admitted to a general public hospital ward. Methods: This prospective study enrolled patients (≥18 years old) admitted to a medical ward with a primary diagnosis of acute HF directly from the emergency department. CRP was measured within 72 […]

Abstract Background: Cardiovascular diseases (CVDs) are the leading cause of death in the world, and companies can implement prevention and control actions aimed at reducing risk factors among their workers. Objectives: To verify whether the result of model A of a CVD prevention and control program was superior to model B in reducing the cardiovascular risk (CVR) of individuals from an oil company. Methods: Retrospective evaluation of secondary data from a restricted and fixed cohort of 670 workers, from 01/01/2016 […]

Abstract Background: The One-Minute Step Test (1MST) seems to be a useful tool for exploring the component of energy metabolism used in Activities of Daily Living (ADL), but it is still little explored in patients with Heart Failure (HF) in the hospital environment. Objective: To evaluate the feasibility and safety of performing 1MST in hospitalized patients with HF. Methods: Data were collected using electronic medical records and evaluative tests from patients with HF. The safety of the 1MST was assessed […]

Abstract Background: Cardiovascular diseases are the leading cause of mortality worldwide. Wine consumption has been associated with cardiovascular benefits, which are attributed to the presence of flavonoids. Objectives: To assess the effects of alcoholic and non-alcoholic red wine on endothelial function by measuring variations in brachial artery flow-mediated dilation (FMD) and analyzing changes in arterial diameter, heart rate, and blood pressure. Methods: A randomized, parallel, controlled clinical trial was conducted with 22 participants assessed at 2 distinct time points. Participants […]

Abstract Introduction: Cardiovascular diseases (CVDs) remain among the leading causes of morbidity and mortality worldwide, posing a significant public health challenge. Thus, analyzing their prevalence over time is crucial. Objective: To perform an epidemiological analysis of emergency hospital admissions due to CVD in Brazil between 2013 and 2023. Methods: This is an ecological, descriptive study based on data from the DATASUS database. Cardiovascular morbidities classified by ICD-10, along with variables such as sex and age group, were selected for analysis. […]

Abstract Background: Large language models (LLMs) have made a significant impact in medicine and demonstrate substantial promise for further development. However, most of the existing research has predominantly centered on English-language tasks with lower medical complexity. This underscores the importance of investigating the performance of state-of-the-art LLMs in more complex specialties, such as cardiology, and in languages beyond English, such as Portuguese. Objective: This study aimed to evaluate and compare leading LLMs based on their performance on the validated cardiology […]

Abstract Background: Patients with chronic heart failure (HF) require outpatient monitoring after hospital discharge. The ability to use a smartphone with a personal messaging application may help. Objectives: Tis study aimed to investigate the feasibility of remote monitoring and evaluate its impact on treatment adherence and prognosis in patients with HF. Methods: A total of 100 patients were enrolled in the study: 57 patients in the mHealth group and 43 in the control group. The observation period lasted six months. […]