International Journal of Cardiovascular Sciences. 29/Jul/2024;37:e20240051.
Pyrophosphate Scintigraphy: Use in the Diagnosis and Monitoring of Cardiac Amyloidosis
Claudio Tinoco Mesquita
, Davi Shunji Yahiro
, José Felipe Ramos dos Santos
, Luís Eduardo Machado
, Jose Gregorio Valero Rodriguez
, Giovane Leal de Azevedo Junior
, Marcus Simões
Abstract
Cardiac amyloidosis (CA) is a progressive condition marked by the accumulation of amyloid fibrils in cardiac tissue, resulting in cardiac dysfunction and, ultimately, heart failure. Pyrophosphate scintigraphy has emerged as a promising tool for the early detection and monitoring of CA, providing valuable insights into the disease’s extent and severity. This review examines the current use of pyrophosphate scintigraphy in distinguishing between different types of amyloidosis, assessing risk levels, and monitoring patients with CA. It underscores the clinical significance and prospects of this imaging technique.
Keywords: Amyloidosis; Radionuclide Imaging; Diagnosis; Nuclear Medicine
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