Abstract Acute cardiac injury is associated with higher mortality in patients with the novel coronavirus disease-2019 (COVID-19) and the exact etiology can be challenging to diagnose in the emergency setting during the pandemic. From a pathophysiological perspective, SARS-CoV-2 infection is characterized by an overproduction of inflammatory cytokines (IL-6, TNF-alpha) that leads to systemic inflammation and consequent increased risk of acute myocardial infarction (AMI) caused by atheromatous plaque rupture and significant myocardial oxygen supply-demand imbalance. Moreover, SARS-CoV-2 tropism to the renin-angiotensin-aldosterone […]

Dear Editor, We congratulate the authors on the viewpoint entitled “Should Physical Activity Be Considered Essential During the COVID-19 Pandemic?”, and we are thankful for the opportunity to provide some contributions on this current and relevant topic. […]

Medical residency programs were first established in 1889 in Baltimore, Maryland, at John Hopkins University. At the time, Dr. William Healstead realized that seriously ill patients treated by recently certified clinicians had higher mortality rates. In response to this, and in the hopes of increasing the quality and success rates of patient care, Healstead created a new type of training program, in which emerging clinicians would receive their final training in the hospital environment itself. This model, replicated globally, is […]

Introduction Since December 31, 2019, when China reported the appearance of cases of acute respiratory failure caused by a new species of coronavirus, SARS-CoV-2, which causes the disease called COVID-19, almost 20 million cases were confirmed, causing 726 thousand deaths worldwide. In Brazil, on August 8th, 2020, there was approximately 3 million cases and 100 thousand death by the disease. Its rapid spread, its high potential for hospitalization, and its high lethality, especially in the most fragile groups such as […]

Abstract Background Lung ultrasound (LUS) can detect interstitial alveolar changes confined to the subpleural region, like those described in Covid-19. Objetive To evaluate how LUS findings correlate with chest computed tomography (CT) in patients admitted to the emergency department (ED) with suspicion of Covid-19. Methods Cross-sectional study of 20 patients (median age 43 years; interquartile range, 37–63 years; 50% male). All patients underwent LUS and chest CT on the day of ED admission. Each hemithorax was divided into 6 segments […]

In July 2020, Brazil has the world’s second highest Covid-19 death toll. The COVID-19 pandemic is spreading fast in America. Since the first case of COVID-19 was confirmed, it took 114 days in Brazil (February 26-June 19) and 98 days in the USA (January 21-April 29) for the number of cases to reach more than 1,000,000. Parallel to the rapid growth of COVID-19 cases, there has been a progression in the number of scientific publications. Until June 2020, more than […]

Introduction Cardiovascular diseases (CVD) are the main cause not only of global mortality but also of reduced quality of life. They cover ischemic heart disease, stroke, heart failure, peripheral artery disease, and various other heart and vascular conditions. In 2017, CVDs caused about 17.8 million deaths worldwide, corresponding to 330 million years of life lost and another 35.6 million years of life with disabilities. Almost 80% of deaths occur in low- and middle-income countries, such as Brazil, where the occurrence […]

Introduction The ongoing pandemic of Severe Acute Respiratory Virus-2 (SARS-CoV2) infection was first recognized in China in 2019 and brought significant health and economic threats around the world. On January 31, 2020, the World Health Organization (WHO) declared the disease caused by SARS-CoV2 an international public health emergency and on March 11, 2020, the WHO declared it a pandemic. , Three months after the initial WHO declaration, there are more than 5 million confirmed cases worldwide and 300,000 deaths. In […]

Introduction The current global pandemic caused by the new coronavirus (COVID-19) already reaches 185 countries with approximately 3 million infected people and more than 200 thousand deaths. , With continental dimensions and an elevated socioeconomic disparity, Brazil, by the beginning of May, presents with increasing infection rates and mortality close to 8%. The numbers may be higher considering the lack of adequate testing of the population and healthcare professionals. According to the World Health Organization (WHO), cardiovascular diseases represent the […]