Abstract Background: Trimethylamine N-oxide (TMAO), a gut microbiota metabolite, is associated with cardiovascular disease (CVD) development. TMAO can trigger an inflammatory response by inducing the nuclear factor-kappa B (NF-κB) signaling cascade and increasing the expression of pro-inflammatory cytokines, contributing to the worsening of CVD. This study aimed to evaluate the association between TMAO plasma levels and inflammation in patients with coronary artery disease (CAD). Methods: A cross-sectional study was carried out including 29 patients with CAD. Peripheral blood mononuclear cells […]

Exposure to environmental pollution is a key factor in the development and worsening of cardiovascular diseases. This alert was issued in a 2004 statement from the American Heart Association (AHA). A large body of new scientific evidence has been accumulated since then, allowing for a better understanding of the aspects related to this modifiable risk factor for cardiovascular diseases. […]

Abstract Background: Studies have shown that chronic administration of green tea decreases blood pressure (BP) at rest, while a single exercise session also promotes reduction of BP. Objective: To investigate whether if a single dose of green tea prior to aerobic exercise session improves post-exercise hypotension (PEH). Methods: Randomized, double-blind, placebo controlled study. Fifteen hypertensive patients (53 ± 3.3 years) participated in two study sessions: green tea+exercise (GTE) and placebo+exercise (PLE). Thirty minutes after ingesting 2 g of green tea […]