A bimonthly publication part of the Brazilian Society of Cardiology portfolio of journals connected with ABC Cardiol publishing national and international scientific production in the field of cardiovascular sciences.
ISSN 2359-4802
eISSN 2359-5647
Arini Rizky Wijayanti, Dyah Samti Mayasari
, Erika Maharani
, Hasanah Mumpuni
, Sofia Pranacipta
, [...]
Arini Rizky Wijayanti, Dyah Samti Mayasari
, Erika Maharani
, Hasanah Mumpuni
, Sofia Pranacipta
, [...]
Abstract Background: Rheumatic heart disease (RHD) is the leading cause of valve disease in developing countries, with intracardiac thrombus events as one of the frequent manifestations. Based on Trias Virchow, a thrombus occurs because of endothelial injury, blood flow abnormality, and hypercoagulability. In RHD, this condition is caused by inflammation, mitral stenosis (MS), and atrial fibrillation (AF). Pro-inflammatory cytokines promote thrombus formation, and anti-inflammatory cytokines inhibit it. IL-4 is an anti-inflammatory cytokine that can potentially inhibit thrombus formation because it […]
Keywords: Interleukin-4; Thrombosis; Atrial Fibrillation; Rheumatic Heart Disease