Introduction Endothelium regulates cardiac function and vasomotor tone, adjusts vascular permeability, preserves blood fluidity, playing an important role in cardiovascular homeostasis., In adults with heart failure (HF), endothelial dysfunction severity is related to diastolic dysfunction,, increase in cardiovascular risk,– heart failure,, exercise incapacity, severity of cardiovascular symptoms,,,,, cardiovascular events, cardiac transplant and death., Although endothelium is at the interface between circulating cardiovascular factors and underlying organ tissues, cardiovascular and endothelial peripheral dysfunctions are not totally linked so far.– Evaluation of […]